Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429187 | 0.82 | PTPN1 (0.48) | NPC1RAB9AKMT2AMEN1NAMPT | |
| SCHEMBL7641330 | 0.80 | NPC1 (0.53) | NPC1RAB9AALDH1A1NAMPTLMNA | |
| SCHEMBL7641652 | 0.80 | MEN1 (0.59) | NPC1RAB9AKMT2AMEN1CYP11B1 | |
| SCHEMBL11490610 | 0.80 | NPC1 (0.53) | NPC1RAB9AKMT2AMEN1CYP11B1 | |
| SCHEMBL8417469 | 0.77 | MMP1 (0.65) | NPC1RAB9AKMT2AMEN1CYP11B1 | |
| SCHEMBL10933418 | 0.76 | CACNA1B (0.64) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7640108 | 0.76 | F10 (0.62) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL3190254 | 0.76 | MEN1 (0.68) | NPC1RAB9AKMT2AMEN1CYP11B1 | |
| SCHEMBL7644336 | 0.75 | MEN1 (0.57) | NPC1RAB9AKMT2AMEN1CYP11B1 | |
| SCHEMBL3195302 | 0.74 | MLYCD (0.63) | NPC1RAB9AKMT2AMEN1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469003-B1 | COMPOUNDS HAVING CELL ADHESION INHIBITING ACTIVITY | NIHON NOHYAKU CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1130015-A1 | PYRIDAZINONE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2001-09-05 | — | — | EP | disclosed |