Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28904178 | 0.89 | RAB9A (0.65) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3753090 | 0.89 | HDAC1 (0.68) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8623142 | 0.87 | DHODH (0.68) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28636436 | 0.85 | RXFP1 (0.59) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8714750 | 0.85 | MLYCD (0.63) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3190254 | 0.84 | MEN1 (0.68) | KMT2AMEN1NPC1RAB9ACYP11B1 | |
| SCHEMBL7110787 | 0.83 | TSHR (0.68) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28857391 | 0.83 | RXFP1 (0.55) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4968034 | 0.82 | MMP1 (0.55) | MMP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13210703 | 0.81 | RAB9A (0.65) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |