Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648833 | 0.90 | CA1 (0.41) | CA1CA2 | |
| SCHEMBL3160042 | 0.82 | CA1 (0.38) | CA1CA2TTR | |
| Methylene Chloride SCHEMBL31173785 | 0.82 | TSHR (0.36) | CALM1SIGMAR1 | |
| SCHEMBL9608259 | 0.80 | CALM1 (0.55) | CA1CA2CALM1 | |
| SCHEMBL759390 | 0.79 | ALDH1A1 (0.38) | CA1CA2CALM1 | |
| SCHEMBL12762137 | 0.79 | ALDH1A1 (0.38) | CA1CA2CALM1 | |
| SCHEMBL12017238 | 0.78 | CALM1 (0.60) | CA1CA2CALM1 | |
| SCHEMBL3190141 | 0.76 | TSHR (0.59) | CA1CA2TTR | |
| SCHEMBL246109 | 0.76 | TP53 (0.59) | TAAR1 | |
| SCHEMBL686320 | 0.76 | TSHR (0.59) | CA1CA2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479210-B2 | COMPRISING AN ORGANIC MATERIAL CONTAINING SUBSTITUENT(S) CAPABLE OF BEING RELEASED IN THE PRESENCE OF ACID, AND ACID GENERATORS OF AT LEAST ONE ONIUM SALT AND SULFONE AND/OR SULFONATE COMPOUNDS; RESOLUTION, SENSITIVITY | CLARIANT FINANCE (BVI) LIMITED (VG) | 2002-11-12 | — | — | US | claimed |