Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 7/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468815 | 0.77 | ALDH1A1 (0.57) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL966067 | 0.77 | ALDH1A1 (0.57) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL10473188 | 0.76 | PIM1 (0.43) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7489369 | 0.75 | STAT3 (0.40) | ALDH1A1TOP2ATOP2BPIM1GSK3A | |
| SCHEMBL7855602 | 0.75 | ALDH1A1 (0.39) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL1844834 | 0.72 | ALDH1A1 (0.43) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL8912577 | 0.72 | PIM1 (0.48) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7646010 | 0.72 | ALDH1A1 (0.47) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL5704368 | 0.72 | STAT3 (0.56) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL30863948 | 0.72 | STAT3 (0.56) | ALDH1A1POLBCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462218-B1 | BY HYDROLYTIC CLEAVAGE CARRIED OUT IN THE PRESENCE OF ACIDS AND WATER OF ITS AMIDE, ESTER OR CYANO DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |