Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 7/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468815 | 1.00 | ALDH1A1 (0.57) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6659404 | 0.89 | TOP2A (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL30891255 | 0.89 | TOP2A (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7646010 | 0.87 | ALDH1A1 (0.47) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL13470136 | 0.87 | TOP2A (0.58) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL1844834 | 0.86 | ALDH1A1 (0.43) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9149649 | 0.85 | TOP2A (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL5704368 | 0.85 | STAT3 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL30863948 | 0.85 | STAT3 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL25669903 | 0.84 | ALDH1A1 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | claimed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | claimed |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-03-18 | — | — | US | claimed |
| EP-3784656-A1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | Bayer Animal Health GmbH (DE) | 2021-03-03 | — | — | EP | claimed |
| CN-111989314-A | Process for hydrolysis of quinolone formates | 拜耳动物保健有限责任公司 | 2020-11-24 | — | — | CN | claimed |
| EP-2086976-B1 | METHOD FOR PRODUCING PRADOFLOXACIN | BAYER ANIMAL HEALTH GMBH (DE) | 2011-05-18 | — | — | EP | claimed |
| US-20090318700-A1 | PROCESS FOR PREPARING PRADOFLOXACIN | ELANCO ANIMAL HEALTH GMBH (DE) | 2009-12-24 | — | — | US | claimed |
| EP-2086976-A1 | METHOD FOR PRODUCING PRADOFLOXACIN | Bayer Animal Health GmbH (DE) | 2009-08-12 | — | — | EP | claimed |
| WO-2008046532-A1 | METHOD FOR PRODUCING PRADOFLOXACIN | BAYER ANIMAL HEALTH GMBH (DE) | 2008-04-24 | — | — | WO | claimed |
| CN-111989314-B | Method for hydrolyzing quinolone formate | 拜耳动物保健有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117849219-A | Method for detecting content of pramipexole | 上海汉维生物医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | disclosed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | disclosed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | disclosed |
| WO-1997031001-A1 | POSSIBLY SUBSTITUTED 8-CYANO-1-CYCLOPROPYL-7-(2,8-DIAZABICYCLO-[4.3.0]-NONAN-8-YL)-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLIN CARBOXYLIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-28 | — | — | WO | disclosed |
| EP-0704443-A2 | Quinolone and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| US-5190955-A | Bactericides, effective against antibiotic resistant germs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5051418-A | Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| US-4908366-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318700-A1 | PROCESS FOR PREPARING PRADOFLOXACIN | CYP3A4, CYP3A5, CYP3A7 | ALDH1A1 971/4885POLB 102/4885OPRM1 689/4885 |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | NQO2, PGD, ALAD | ALDH1A1 274/4885POLB 172/4885OPRM1 2751/4885 |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | NQO2, PGD, ALAD | ALDH1A1 274/4885POLB 172/4885OPRM1 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.