Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464860 | 0.91 | — | — | |
| Acetic Acid SCHEMBL10764981 | 0.88 | TSHR (0.47) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| Alcohol SCHEMBL28176785 | 0.83 | TSHR (0.55) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| Chloromethane SCHEMBL28100228 | 0.78 | TSHR (0.55) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL194711 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL4793964 | 0.76 | — | — | |
| Ethylene SCHEMBL7133194 | 0.76 | TSHR (0.57) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| Alcohol SCHEMBL18290914 | 0.76 | TSHR (0.47) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27874012 | 0.76 | — | — | |
| Water SCHEMBL28111613 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053400-B2 | Liquid cleansing composition comprising a ternary mixture of anionic surfactants | STEPAN COMPANY (US) | 2011-11-08 | — | — | US | claimed |
| US-20090227482-A1 | LIQUID CLEANSING COMPOSITION | STEPAN COMPANY | 2009-09-10 | — | — | US | claimed |
| EP-4240317-A1 | PERSONAL CLEANSING COMPOSITIONS WITH SURFACTANTS FOR INCREASED FOAM PERFORMANCE | Ecolab USA Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099114-A1 | PERSONAL CLEANSING COMPOSITIONS WITH SURFACTANTS FOR INCREASED FOAM PERFORMANCE | ECOLAB USA INC. (US) | 2022-05-12 | — | — | WO | disclosed |
| US-20220142879-A1 | PERSONAL CLEANSING COMPOSITIONS WITH SURFACTANTS FOR INCREASED FOAM PERFORMANCE | ECOLAB USA INC. | 2022-05-12 | — | — | US | disclosed |
| EP-2431019-B1 | Personal liquid cleansing composition | STEPAN CO (US) | 2016-07-13 | — | — | EP | disclosed |
| EP-2431019-A1 | Personal liquid cleansing composition | STEPAN COMPANY (US) | 2012-03-21 | — | — | EP | disclosed |
| US-8053400-B2 | Liquid cleansing composition comprising a ternary mixture of anionic surfactants | STEPAN COMPANY (US) | 2011-11-08 | — | — | US | disclosed |
| US-20090227482-A1 | LIQUID CLEANSING COMPOSITION | STEPAN COMPANY | 2009-09-10 | — | — | US | disclosed |
| EP-1868558-A1 | LIQUID CLEANSING COMPOSITION | STEPAN COMPANY (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006084190-A1 | LIQUID CLEANSING COMPOSITION | STEPAN COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227482-A1 | LIQUID CLEANSING COMPOSITION | CUTA, SMURF1, FAAH | TSHR 3360/4885TDP1 1609/4885CYP3A4 1998/4885 |
| US-20220142879-A1 | PERSONAL CLEANSING COMPOSITIONS WITH SURFACTANTS FOR INCREASED FOAM PERFORMANCE | AGPS, CUTA, SMURF1 | TSHR 3898/4885TDP1 1921/4885CYP3A4 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.