Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641797 | 1.00 | MAPT (0.50) | MAPTESR1GAACYP19A1CYP11B2 | |
| SCHEMBL28880691 | 0.86 | ESR1 (0.61) | MAPTESR1GAACYP19A1CYP11B2 | |
| SCHEMBL4612461 | 0.86 | ESR1 (0.59) | MAPTESR1CYP19A1CYP11B2PTGS2 | |
| SCHEMBL4612464 | 0.86 | ESR1 (0.59) | MAPTESR1CYP19A1CYP11B2PTGS2 | |
| SCHEMBL8927508 | 0.81 | MAPT (0.54) | MAPTKDM4ETRPA1 | |
| SCHEMBL29965663 | 0.80 | MAPT (0.53) | MAPTGAAKMT2AKDM4E | |
| SCHEMBL5945849 | 0.80 | ESR1 (0.53) | ESR1CYP19A1CYP11B2PTGS2AKR1C1 | |
| SCHEMBL17967368 | 0.80 | MAPT (0.47) | MAPTESR1GAACYP19A1CYP11B2 | |
| SCHEMBL20799495 | 0.80 | PTGS2 (0.44) | MAPTESR1CYP19A1CYP11B2PTGS2 | |
| SCHEMBL17967362 | 0.80 | SMN1; SMN2 (0.44) | MAPTESR1CYP19A1CYP11B2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947561-B1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6235861-B1 | REACTION INHIBITOR IS ADDED TO THE COMPOSITION COMPRISING AN ALKENYLATED ORGANOPOLYSILOXANE, AN ORGANOHYDROGENPOLYSILOXANE, AND A PLATINUM CATALYST. | THREE BOND (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0947561-A1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |