Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641797 | 0.81 | MAPT (0.50) | MAPTKDM4ETRPA1 | |
| SCHEMBL7646238 | 0.81 | MAPT (0.50) | MAPTKDM4ETRPA1 | |
| SCHEMBL17967351 | 0.81 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1HPGDHDAC2 | |
| SCHEMBL17967352 | 0.81 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1HPGDHDAC2 | |
| SCHEMBL17967344 | 0.81 | MAPT (0.49) | MAPTKDM4EALDH1A1HPGDBCHE | |
| SCHEMBL17967346 | 0.81 | MAPT (0.49) | MAPTKDM4EALDH1A1HPGDBCHE | |
| SCHEMBL1304425 | 0.79 | MAPT (0.85) | MAPTKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL8049692 | 0.79 | MAPT (0.85) | MAPTKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL8049689 | 0.79 | MAPT (0.85) | MAPTKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL1304422 | 0.79 | MAPT (0.85) | MAPTKDM4EALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672728-A | FORMYLATION | RICOH COMPANY, LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| US-5616805-A | USING A PYRENYLAMINE COMPOUND CONTAINING AN ALDEHYDE GROUP AS CHEMICAL INTERMEDIATE | RICOH COMPANY, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5599995-A | Electrophotographic photoconductor comprising pyrenylamine derivative, the pyrenylamine derivative, intermediate for preparation thereof, and method for preparing the pyrenylamine derivative and the intermediate | RICOH COMPANY, LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5587516-A | REACTING SECONDARY AMINE COMPOUND WITH PYRENE COMPOUND | RICOH COMPANY, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5576132-A | ELECTROGRAPHIC PHOTOCONDUCTOR WITH ELECTROCONDUCTIVE SUBSTRATE WITH PYRENYLAMINE DERIVATIVES | RICOH COMPANY, LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| US-5459275-A | Photoconductive layer on electroconductive substrate; electrography; durability, heat resistance, shockproof, flexibility | RICOH COMPANY, LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| US-5457232-A | Photoconductive material for electrophotography | RICOH COMPANY, LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| US-5344985-A | Photoconductors for electrophotography | RICOH COMPANY, LTD. (JP) | 1994-09-06 | — | — | US | disclosed |