Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245663 | 0.68 | HSD17B10 (0.38) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL28786979 | 0.67 | HSD17B10 (0.40) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL12480441 | 0.67 | HTT (0.53) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL17898549 | 0.66 | IDO1 (0.40) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL9227344 | 0.64 | ALDH1A1 (0.38) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL145905 | 0.62 | TSHR (0.46) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL6745338 | 0.62 | HSD17B10 (0.37) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL3396411 | 0.61 | MAP3K14 (0.39) | HSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL11666010 | 0.60 | ALDH1A1 (0.53) | HSD17B10LMNAGAAMAPTHTT | |
| SCHEMBL2162536 | 0.60 | ALDH1A1 (0.42) | HSD17B10LMNAMAPTTSHRRGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472227-B1 | A FLUORESCEIN MOIETY IS INCLUDED IN THE TRACER, WHILE A POLY(AMINO ACID) FORMS A PART OF THE IMMUNOGEN FOR DETERMINING THE AMOUNT OF BARBITURATE IN FLUIDS, ESPECIALLY BIOLOGICAL FLUIDS SUCH AS SERUM, PLASMA OR URINE | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| EP-0457213-B1 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LAB (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0457213-A2 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0373508-A2 | Barbiturate assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1990-06-20 | — | — | EP | disclosed |