Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411779 | 0.76 | ALDH1A1 (0.35) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL17594901 | 0.72 | GRIK1 (0.36) | GRIK1GRIK2USP2ALDH1A1LMNA | |
| SCHEMBL8028102 | 0.69 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2DPP4FAP | |
| SCHEMBL14677430 | 0.69 | GRIK1 (0.36) | GRIK1GRIK2USP2ALDH1A1LMNA | |
| SCHEMBL8670866 | 0.67 | CYP2C19 (0.38) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL27360095 | 0.67 | ALDH1A1 (0.35) | GRIK1USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL7646569 | 0.67 | CYP2C19 (0.38) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL22963815 | 0.66 | MME (0.35) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL6567364 | 0.66 | ALDH1A1 (0.37) | GRIK1GRIK2USP2ALDH1A1LMNA | |
| SCHEMBL3336186 | 0.66 | ALDH1A1 (0.37) | GRIK1GRIK2USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29324-E | N-Substituted aspartyl peptide amides | G. D. SEARLE & CO. (US) | 1977-07-26 | — | — | US | disclosed |