Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Methyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.35 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.35 |
| ▸ | CACNA1B known ✓ | Q00975 | 1/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL341831 | 0.95 | — | — | |
| Alcohol SCHEMBL28117603 | 0.92 | ALDH1A1 (0.46) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 | |
| Methyl Alcohol SCHEMBL4500223 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 | |
| Methyl Alcohol SCHEMBL6383962 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 | |
| Water SCHEMBL104604 | 0.91 | — | — | |
| Water SCHEMBL20920097 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 | |
| Water SCHEMBL812316 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 | |
| Water SCHEMBL812317 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 | |
| Water SCHEMBL11589729 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 | |
| Water SCHEMBL27670879 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114509513-B | Liquid chromatography high-resolution mass spectrometry qualitative and quantitative detection method for bile acid in multiple tissues | 中国农业科学院饲料研究所 | 2022-11-15 | — | — | CN | claimed |
| CN-114509513-A | Liquid chromatography high-resolution mass spectrometry qualitative and quantitative detection method for bile acid in multiple tissues | 中国农业科学院饲料研究所 | 2022-05-17 | — | — | CN | claimed |
| CN-104788375-B | Method for separating 8-deoxidized lappaconitine | 新疆医科大学附属中医医院 | 2017-02-22 | — | — | CN | claimed |
| CN-104788374-A | Method for separating aconitum leucostomum alkaloid | AFFILIATED TRADITIONAL CHINESE MEDICINE HOSPITAL OF XINJIANG MEDICAL UNIVERSITY | 2015-07-22 | — | — | CN | claimed |
| CN-104788375-A | Method for separating 8-deoxidized lappaconitine | AFFILIATED TRADITIONAL CHINESE MEDICINE HOSPITAL OF XINJIANG MEDICAL UNIVERSITY | 2015-07-22 | — | — | CN | claimed |
| CN-102749401-B | Inspection method of traditional Chinese medicine composition twenty-five-ingredient lung disease preparation | SHANDONG ARURA PHARMACEUTICAL RES & DEV CO LTD | 2013-12-18 | — | — | CN | claimed |
| CN-102944618-A | Content detection method of Chinese medicine preparation for treating gastropathy | GUANGXI MEDICTOP PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | claimed |
| CN-1850059-A | Amlexanox oral membrane, and its preparing method | WANG FAPING (CN) | 2006-10-25 | — | — | CN | claimed |
| CN-1660051-A | Method for preparing bath powder of Tibet medicine and its quality control method | YUTUO TIBET MEDICINE RES CO LT (CN) | 2005-08-31 | — | — | CN | claimed |
| US-4359460-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1982-11-16 | — | — | US | claimed |
| CN-116297908-B | Analysis method of indobufen isomer impurity | 湖南九典制药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117756721-A | Co-crystal of dibazoles and tartaric acid as well as preparation and application thereof | 浙江方锘制药有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117740969-A | Indolibuprfen impurity detection method and application thereof | 杭州志呈科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117430557-A | Preparation and application of eutectic crystal form of dibazoles and mandelic acid and pharmaceutical composition | 上海应用技术大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-117430558-A | Preparation and application of drug-drug co-crystal of dibazol hydrochloride and atenolol and drug composition | 上海应用技术大学 | 2024-01-23 | — | — | CN | disclosed |
| US-4181685-A | Thermoplastic molding compositions on the basis of polyoxymethylenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-01 | — | — | US | disclosed |
| US-4159964-A | Metal chelate catalyst and alkanolamine hydroxide on adsorptive support | UOP INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-4127474-A | Treating a petroleum distillate with an alkanolamine hydroxide and a supported oxidation catalyst impregnated with polynuclear aromatic sulfonic acid | UOP INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4124494-A | Treating a petroleum distillate with a supported metal phthalocyanine and an alkanolamine hydroxide | UOP INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4070415-A | Thermoplastic molding compositions on the basis of polyoxymethylenes | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-24 | — | — | US | disclosed |