Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.60 |
| ▸ | CTSK | P43235 | 4/20 | 0.60 |
| ▸ | CTSB | P07858 | 4/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | FCER2 | P06734 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646982 | 1.00 | CTSS (0.60) | CTSSCTSKCTSBATMFCER2 | |
| SCHEMBL7650106 | 0.87 | FCER2 (0.59) | CTSSCTSKCTSBFCER2CTSL | |
| SCHEMBL7651306 | 0.87 | FCER2 (0.59) | CTSSCTSKCTSBFCER2CTSL | |
| SCHEMBL5966507 | 0.86 | CTSS (0.74) | CTSSCTSKCTSBFCER2CTSL | |
| SCHEMBL5557866 | 0.86 | CTSS (0.74) | CTSSCTSKCTSBFCER2CTSL | |
| SCHEMBL7333181 | 0.81 | ATM (0.70) | CTSSCTSKCTSBATMAPP | |
| SCHEMBL18645283 | 0.81 | ATM (0.70) | CTSSCTSKCTSBATMAPP | |
| SCHEMBL7333186 | 0.81 | ATM (0.70) | CTSSCTSKCTSBATMAPP | |
| SCHEMBL7366802 | 0.79 | CTSS (0.60) | CTSSCTSKCTSBFCER2CTSL | |
| SCHEMBL14332332 | 0.79 | CTSS (0.62) | CTSSCTSKCTSBATMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184370-A2 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2002-03-06 | — | — | EP | disclosed |
| US-6274584-B1 | PEPTIDE DERIVATIVES; BIOAVAILABILITY; ENZYME RESISTANCE; MILK AND WOOL PRODUCTION | NOVO NORDISK A/S (DK) | 2001-08-14 | — | — | US | disclosed |
| US-6127354-A | FOR TREATMENT OF GROWTH DISORDERS OR TO STIMULATE PRODUCTION OF WOOL OR MILK | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| US-5922770-A | NOVEL COMPOUNDS THAT STIMULATE THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY | NOVO NORDISK A/S (DK) | 1999-07-13 | — | — | US | disclosed |