Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.60 |
| ▸ | CTSK | P43235 | 6/20 | 0.60 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | FCER2 | P06734 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428281 | 0.86 | GHSR (0.49) | CTSSCTSKCTSBPTPN1FCER2 | |
| SCHEMBL7368069 | 0.86 | GHSR (0.49) | CTSSCTSKCTSBPTPN1FCER2 | |
| SCHEMBL4426088 | 0.85 | FCER2 (0.53) | CTSSCTSKCTSBCTSLFCER2 | |
| SCHEMBL4427112 | 0.85 | FCER2 (0.53) | CTSSCTSKCTSBCTSLFCER2 | |
| SCHEMBL6317992 | 0.85 | FCER2 (0.53) | CTSSCTSKCTSBCTSLFCER2 | |
| SCHEMBL6323402 | 0.84 | CTSS (0.47) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL5557866 | 0.84 | CTSS (0.74) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL5966507 | 0.84 | CTSS (0.74) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL6323403 | 0.83 | CTSS (0.46) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL5552762 | 0.82 | CTSS (0.64) | CTSSCTSKCTSBPTPN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941115-A1 | USE OF GROWTH HORMONE OR A GROWTH HORMONE SECRETAGOGUE FOR PROMOTING BONE FORMATION | NOVO NORDISK A/S (DK) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998019699-A1 | USE OF GROWTH HORMONE OR A GROWTH HORMONE SECRETAGOGUE FOR PROMOTING BONE FORMATION | NOVO NORDISK A/S (DK) | 1998-05-14 | — | — | WO | disclosed |