SCHEMBL7647175

SCHEMBL7647175

CC(=O)Nc1cc(Cl)c([N+](=O)[O-])cc1OCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.67
BRD4 O60885 11/20 0.56
CTSV O60911 2/20 0.49
CTSL P07711 2/20 0.49
MYC P01106 1/20 0.48
MAX P61244 1/20 0.48
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
CXCR2 P25025 1/20 0.46
PPIA P62937 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5734406 0.88 MYC (0.55) CYP19A1CTSVCTSLMYCMAX
SCHEMBL7650190 0.86 CYP19A1 (0.67) CYP19A1BRD4CTSVCTSLMYC
SCHEMBL7647773 0.81 CYP19A1 (0.60) CYP19A1BRD4CTSVCTSLMEN1
SCHEMBL2568216 0.80 PIN1 (0.52) CYP19A1CTSVCTSLMEN1MAPT
SCHEMBL5381129 0.80 CYP19A1 (1.00) CYP19A1BRD4MEN1MAPTKMT2A
SCHEMBL28534643 0.80 CYP19A1 (0.57) CYP19A1BRD4CTSVCTSLMYC
SCHEMBL11447660 0.79 CHEK1 (0.56) MEN1MAPTKMT2A
SCHEMBL7146338 0.79 CYP19A1 (0.57) CYP19A1BRD4CTSVCTSLMYC
SCHEMBL3110737 0.78 MEN1 (0.53) CTSVCTSLMEN1MAPTKMT2A
SCHEMBL9581484 0.78 SLC9A1 (0.46) CYP19A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6482985-B1 2-benzyloxy-5-halo-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2002-11-19 US disclosed