Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.67 |
| ▸ | BRD4 | O60885 | 11/20 | 0.62 |
| ▸ | CTSV | O60911 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | MAX | P61244 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647175 | 0.86 | CYP19A1 (0.67) | CYP19A1BRD4CTSVCTSLMYC | |
| SCHEMBL27238124 | 0.84 | CYP19A1 (0.52) | CYP19A1BRD4PTGESMEN1MAPT | |
| SCHEMBL7647773 | 0.81 | CYP19A1 (0.60) | CYP19A1BRD4CTSVCTSLMEN1 | |
| SCHEMBL810439 | 0.80 | PTGES (0.57) | CYP19A1CTSVCTSLPTGESMEN1 | |
| SCHEMBL30699715 | 0.80 | PTGES (0.57) | CYP19A1CTSVCTSLPTGESMEN1 | |
| SCHEMBL31235944 | 0.80 | CTSV (0.53) | CYP19A1CTSVCTSLPTGESMEN1 | |
| SCHEMBL5381129 | 0.80 | CYP19A1 (1.00) | CYP19A1BRD4MEN1MAPTKMT2A | |
| SCHEMBL6097716 | 0.79 | PTGES (0.54) | CYP19A1CTSVCTSLPTGESMEN1 | |
| SCHEMBL7146338 | 0.79 | CYP19A1 (0.57) | CYP19A1BRD4CTSVCTSLMYC | |
| SCHEMBL9196201 | 0.79 | ALDH1A1 (0.48) | CYP19A1BRD4MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482985-B1 | 2-benzyloxy-5-halo-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-19 | — | — | US | disclosed |