Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831126 | 0.94 | PAM (0.60) | TSHRPAMAKR1B1GPR84PPARG | |
| Butane SCHEMBL10396228 | 0.93 | TSHR (0.58) | TSHRPAMAKR1B1GPR84PPARG | |
| SCHEMBL7645974 | 0.91 | ALDH1A1 (0.55) | TSHRPAMALDH1A1TDP1MEN1 | |
| SCHEMBL9558119 | 0.89 | SLC22A6 (0.61) | TSHRPAMHDAC3HDAC1HDAC2 | |
| SCHEMBL3834164 | 0.87 | AKR1B1 (0.70) | TSHRPAMAKR1B1GPR84PPARG | |
| SCHEMBL20351230 | 0.86 | FFAR3 (0.55) | TSHRPAMFFAR3HDAC3HDAC1 | |
| SCHEMBL3829618 | 0.85 | PAM (0.71) | TSHRPAMAKR1B1GPR84PPARG | |
| Azelaic Acid SCHEMBL6665373 | 0.85 | PAM (0.71) | TSHRPAMAKR1B1GPR84PPARG | |
| SCHEMBL3836400 | 0.85 | PAM (0.71) | TSHRPAMAKR1B1GPR84PPARG | |
| Sebacic Acid SCHEMBL6661482 | 0.85 | PAM (0.71) | TSHRPAMAKR1B1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0961614-A4 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | UNIV BAR ILAN (IL) | 2002-07-24 | — | — | EP | claimed |
| EP-0961614-A1 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 1999-12-08 | — | — | EP | claimed |
| WO-1998029114-A9 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | — | 1998-10-29 | — | — | WO | claimed |
| WO-1998040078-A1 | THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES | BEACON LABORATORIES, INC. (US) | 1998-09-17 | — | — | WO | claimed |
| WO-1998029114-A1 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 1998-07-09 | — | — | WO | claimed |
| EP-0961614-A4 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | UNIV BAR ILAN (IL) | 2002-07-24 | — | — | EP | disclosed |
| EP-0961614-A1 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 1999-12-08 | — | — | EP | disclosed |
| WO-1998029114-A9 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | — | 1998-10-29 | — | — | WO | disclosed |
| WO-1998040078-A1 | THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES | BEACON LABORATORIES, INC. (US) | 1998-09-17 | — | — | WO | disclosed |
| WO-1998029114-A1 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 1998-07-09 | — | — | WO | disclosed |