Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831128 | 0.92 | DGKA (0.64) | ALDH1A1DGKAPAMCYP1A2TSHR | |
| SCHEMBL2618716 | 0.92 | ALDH1A1 (0.63) | ALDH1A1DGKAPAMCYP1A2TSHR | |
| SCHEMBL7647491 | 0.91 | TSHR (0.56) | ALDH1A1DGKAPAMTSHRTDP1 | |
| Bis(Butyryloxymethyl) Succinate SCHEMBL18747588 | 0.89 | ALDH1A1 (0.60) | ALDH1A1DGKAPAMCYP1A2TSHR | |
| SCHEMBL8460377 | 0.88 | DGKA (0.72) | ALDH1A1DGKAPAMTSHRMAPT | |
| SCHEMBL10099629 | 0.86 | DGKA (0.62) | ALDH1A1DGKAPAMCYP1A2TSHR | |
| SCHEMBL3831126 | 0.84 | PAM (0.60) | ALDH1A1DGKAPAMTSHRMAPT | |
| SCHEMBL8424652 | 0.84 | ALDH1A1 (0.62) | ALDH1A1DGKAPAMCYP1A2TSHR | |
| SCHEMBL10911616 | 0.84 | DGKA (0.74) | ALDH1A1DGKAPAMTSHRMAPT | |
| SCHEMBL3834162 | 0.84 | DGKA (0.74) | ALDH1A1DGKAPAMTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0961614-A4 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | UNIV BAR ILAN (IL) | 2002-07-24 | — | — | EP | claimed |
| US-6130248-A | Tricarboxylic acid-containing oxyalkyl esters and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2000-10-10 | — | — | US | claimed |
| EP-0961614-A1 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 1999-12-08 | — | — | EP | claimed |
| US-5939455-A | Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives | BEACON LABORATORIES, INC. (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998029114-A9 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | — | 1998-10-29 | — | — | WO | claimed |
| WO-1998040078-A1 | THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES | BEACON LABORATORIES, INC. (US) | 1998-09-17 | — | — | WO | claimed |
| WO-1998029114-A1 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 1998-07-09 | — | — | WO | claimed |
| US-6130248-A | Tricarboxylic acid-containing oxyalkyl esters and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2000-10-10 | — | — | US | disclosed |
| US-5939455-A | Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives | BEACON LABORATORIES, INC. (US) | 1999-08-17 | — | — | US | disclosed |
| WO-1998029114-A9 | TRICARBOXYLIC ACID-CONTAINING OXYALKYL ESTERS AND USES THEREOF | — | 1998-10-29 | — | — | WO | disclosed |
| WO-1998040078-A1 | THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES | BEACON LABORATORIES, INC. (US) | 1998-09-17 | — | — | WO | disclosed |