Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 20/20 | 0.81 |
| ▸ | MMP2 | P08253 | 5/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | MMP3 | P08254 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182038 | 1.00 | BMP1 (0.81) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL5760686 | 0.90 | BMP1 (0.69) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL6428360 | 0.90 | BMP1 (1.00) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL6429734 | 0.88 | BMP1 (0.82) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL6430549 | 0.87 | BMP1 (0.73) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL27567205 | 0.87 | BMP1 (0.74) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL27567210 | 0.87 | BMP1 (0.74) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL6179694 | 0.86 | BMP1 (0.64) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL6428262 | 0.86 | BMP1 (0.78) | BMP1MMP2PDE4APDE4BPDE4C | |
| SCHEMBL27567224 | 0.86 | BMP1 (0.78) | BMP1MMP2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1423638-A | Oxazolyl hydroxamic acids as procollagen C-protease inhibitors | PFIZER LTD (US) | 2003-06-11 | — | — | CN | disclosed |
| US-6448278-B2 | ANTISCARRING AGENT | PFIZER INC. | 2002-09-10 | — | — | US | disclosed |
| US-20010021718-A1 | Procollagen C-proteinase inhibitors | PFIZER INC. | 2001-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021718-A1 | Procollagen C-proteinase inhibitors | MMP1, CTSL, PREP | BMP1 166/4885MMP2 16/4885PDE4A 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.