Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105066 | 1.00 | POLB (0.53) | POLBSLC6A3KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL18628997 | 1.00 | POLB (0.53) | POLBSLC6A3KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL34462074 | 1.00 | POLB (0.53) | POLBSLC6A3KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL9967101 | 0.89 | CHRM2 (0.42) | POLBSLC6A3SLC6A4 | |
| SCHEMBL18913409 | 0.89 | CHRM2 (0.42) | POLBSLC6A3SLC6A4 | |
| SCHEMBL5422531 | 0.89 | CHRM2 (0.42) | POLBSLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL4386858 | 0.88 | SLC6A3 (0.41) | POLBSLC6A3SLC6A4 | |
| SCHEMBL17243890 | 0.87 | CHRM2 (0.46) | SLC6A3TSHRMEN1KMT2A | |
| SCHEMBL7647666 | 0.83 | POLB (0.52) | POLBKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL2515949 | 0.83 | POLB (0.52) | POLBKCNQ3KCNQ2KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020526-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN SCIENCES IRELAND UC (IE) | 2016-02-11 | — | — | WO | disclosed |