SCHEMBL1105066

SCHEMBL1105066

COC(=O)C1CC2CCC1C2

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
SLC6A3 Q01959 4/20 0.47
KCNQ3 O43525 1/20 0.45
KCNQ2 O43526 1/20 0.45
KCNQ4 P56696 1/20 0.45
KCNQ5 Q9NR82 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TSHR P16473 1/20 0.44
HSD11B1 P28845 1/20 0.44
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
SLC6A4 P31645 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18628997 1.00 POLB (0.53) POLBSLC6A3KCNQ3KCNQ2KCNQ4
SCHEMBL17518655 1.00 POLB (0.53) POLBSLC6A3KCNQ3KCNQ2KCNQ4
SCHEMBL34462074 1.00 POLB (0.53) POLBSLC6A3KCNQ3KCNQ2KCNQ4
SCHEMBL9967101 0.89 CHRM2 (0.42) POLBSLC6A3SLC6A4
SCHEMBL18913409 0.89 CHRM2 (0.42) POLBSLC6A3SLC6A4
SCHEMBL5422531 0.89 CHRM2 (0.42) POLBSLC6A3SLC6A4
Hydrochloric Acid SCHEMBL4386858 0.88 SLC6A3 (0.41) POLBSLC6A3SLC6A4
SCHEMBL17243890 0.87 CHRM2 (0.46) SLC6A3TSHRMEN1KMT2A
SCHEMBL7647666 0.83 POLB (0.52) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL2515949 0.83 POLB (0.52) POLBKCNQ3KCNQ2KCNQ4KCNQ5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090509-A1 SPIRO HETEROCYCLIC CDK2 INHIBITORS ARCHITECT THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
WO-2025031481-A1 RXFP1 RECEPTOR MODULATOR AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 深圳信立泰药业股份有限公司 2025-02-13 WO disclosed
US-20230359119-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-09 US disclosed
CN-116903791-A Hydrocarbon resin polymer, method for preparing the same, composition comprising the same, and substrate 李长荣化学工业股份有限公司 2023-10-20 CN disclosed
EP-3514221-B1 USE AS A PERFUME MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2022-01-19 EP disclosed
EP-3427738-B1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMA (US) 2021-12-01 EP disclosed
US-10988491-B2 Degradable polymers of a cyclic silyl ether and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-04-27 US disclosed
US-10858367-B2 Compounds GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2020-12-08 US disclosed
US-20200283696-A1 PERFUME COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-09-10 US disclosed
CN-1576272-A Sulfonate and a resist composition SUMITOMO CHEMICAL CO (JP) 2005-02-09 CN disclosed
CN-1527808-A Process for production of fluorine-containing norbornene derivatives ͬ�Ϳ�ҵ��ʽ���� 2004-09-08 CN disclosed
EP-1230241-A2 ADENOSINE RECEPTOR ANTAGONISTS AND METHODS OF MAKING AND USING THE SAME BIOGEN, INC. (US) 2002-08-14 EP disclosed
CN-1347939-A Cycloolefen addition copolymer composition and cross-linked material JSR CORP (JP) 2002-05-08 CN disclosed
WO-2001034604-A2 ADENOSINE RECEPTOR ANTAGONISTS AND METHODS OF MAKING AND USING THE SAME BIOGEN, INC. (US) 2001-05-17 WO disclosed
CN-1190410-A Addition polymers of polycycloolefines containing functional substituents GOODRICH CO B F (US) 1998-08-12 CN disclosed
EP-0402881-B1 Process for improving the coefficient of traction. IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-29 EP disclosed
US-5126065-A PROCESS FOR IMPROVING THE COEFFICIENT OF TRACTION AND TRACTION DRIVE FLUID IDEMITSU KOSAN CO., LTD. (JP) 1992-06-30 US disclosed
EP-0402881-A1 Process for improving the coefficient of traction. IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-12-19 EP disclosed
US-3965132-A DIMERS FROM OLEFINS AND WATER OR ALCOHOL AND CARBON MONOXIDE, TRIFLUOROMETHANESULFONIC ACID PHILLIPS PETROLEUM COMPANY (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10858367-B2 Compounds LRRK2, PARK7, PINK1 POLB 1001/4885SLC6A3 2528/4885KCNQ3 3057/4885
US-10988491-B2 Degradable polymers of a cyclic silyl ether and uses thereof SI, ILK, PCNA POLB 670/4885SLC6A3 4796/4885KCNQ3 4864/4885
US-20200283696-A1 PERFUME COMPOSITION H1-0, H1-2, CUTA POLB 152/4885SLC6A3 4649/4885KCNQ3 685/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 POLB 1910/4885SLC6A3 4858/4885KCNQ3 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.