Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743723 | 0.93 | TRPA1 (0.52) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL29712101 | 0.93 | TRPA1 (0.52) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL30535832 | 0.91 | TRPA1 (0.50) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL7583763 | 0.91 | TRPA1 (0.50) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL31565122 | 0.89 | TRPA1 (0.48) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL2934543 | 0.88 | ALOX15 (0.46) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL6530985 | 0.84 | MYC (0.53) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL22760638 | 0.84 | TRPA1 (0.43) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL13201408 | 0.84 | ALDH1A1 (0.46) | TRPA1ATMMYCMAOAELANE | |
| SCHEMBL4621499 | 0.84 | ALDH1A1 (0.46) | TRPA1ATMMYCMAOAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002018485-A1 | FLAME-RETARDED POLYPHENYLENE ETHER COMPOSITION AND METHOD OF MAKING SAME | GENERAL ELECTRIC COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |