Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 2/20 | 0.48 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.36 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652187 | 0.89 | NQO1 (0.49) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL7652382 | 0.89 | TDP2 (0.49) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL7679049 | 0.87 | NQO1 (0.60) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL7648036 | 0.87 | NQO1 (0.47) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL15698469 | 0.78 | NQO1 (0.76) | NQO1TDP2G6PDNSD2S100A4 | |
| SCHEMBL7648029 | 0.77 | TDP2 (0.58) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL7647843 | 0.75 | TDP2 (0.58) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL7648160 | 0.72 | TDP2 (0.74) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL7678312 | 0.70 | TDP2 (0.60) | NQO1TDP2G6PDNSD2CDC25B | |
| SCHEMBL7654680 | 0.69 | CDC25B (0.60) | NQO1TDP2G6PDNSD2CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064396-A9 | NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING | GEORGETOWN UNIVERSITY (US) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012064396-A2 | NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING | GEORGETOWN UNIVERSITY (US) | 2012-05-18 | — | — | WO | disclosed |