Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.60 |
| ▸ | TDP2 | O95551 | 3/20 | 0.60 |
| ▸ | G6PD | P11413 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 2/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.60 |
| ▸ | S100A4 | P26447 | 6/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.45 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.45 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.45 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647843 | 0.87 | TDP2 (0.58) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL7648160 | 0.81 | TDP2 (0.74) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL7648029 | 0.77 | TDP2 (0.58) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL7678312 | 0.76 | TDP2 (0.60) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL7648238 | 0.74 | S100A4 (0.68) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL15698460 | 0.74 | S100A4 (0.58) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL7679049 | 0.73 | NQO1 (0.60) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL15698498 | 0.71 | NQO1 (0.64) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL7652187 | 0.70 | NQO1 (0.49) | CDC25BTDP2G6PDNSD2DUSP3 | |
| SCHEMBL2599397 | 0.70 | S100A4 (1.00) | CDC25BTDP2G6PDNSD2DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064396-A9 | NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING | GEORGETOWN UNIVERSITY (US) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012064396-A2 | NOVEL EZRIN INHIBITORS AND METHODS OF MAKING AND USING | GEORGETOWN UNIVERSITY (US) | 2012-05-18 | — | — | WO | disclosed |