Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | MPO | P05164 | 6/20 | 0.69 |
| ▸ | XDH | P47989 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | QPCT | Q16769 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293995 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HPGDMPOXDHNPC1 | |
| SCHEMBL10289184 | 0.87 | MPO (0.60) | ALDH1A1HPGDMPOXDHNPC1 | |
| SCHEMBL12713432 | 0.85 | MPO (0.73) | ALDH1A1MPOXDHNPC1RAB9A | |
| SCHEMBL12713472 | 0.83 | KDM4E (0.70) | ALDH1A1HPGDMPOXDHNPC1 | |
| SCHEMBL10288918 | 0.82 | MPO (0.68) | ALDH1A1HPGDMPOXDHNPC1 | |
| SCHEMBL2731546 | 0.82 | MPO (1.00) | ALDH1A1MPOXDHHAVCR2 | |
| SCHEMBL2723795 | 0.81 | MPO (0.92) | ALDH1A1MPOXDHNPC1RAB9A | |
| SCHEMBL8987770 | 0.81 | MPO (0.72) | ALDH1A1HPGDMPOXDHKMT2A | |
| SCHEMBL10288919 | 0.81 | MPO (0.67) | ALDH1A1HPGDMPOXDHNPC1 | |
| SCHEMBL3336435 | 0.80 | SMN1; SMN2 (0.70) | ALDH1A1HPGDMPOXDHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |
| EP-0454060-B1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | DROESSLER KARL PROF DR (DE) | 1996-07-03 | — | — | EP | disclosed |
| US-5306721-A | Immunostimulants, viricides | ARZNEIMITTELERK DRESDEN G.M.B.H. (DE) | 1994-04-26 | — | — | US | disclosed |
| EP-0454060-A1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-10-30 | — | — | EP | disclosed |