Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648889 | 0.90 | GRIN1 (0.32) | GRIN1 | |
| SCHEMBL7198556 | 0.89 | CA12 (0.33) | GRIN1 | |
| SCHEMBL7199614 | 0.89 | EGLN1 (0.30) | GRIN1 | |
| SCHEMBL7647196 | 0.86 | KMT2A (0.33) | GRIN1TAS2R14 | |
| SCHEMBL7647232 | 0.85 | KDM4E (0.31) | — | |
| SCHEMBL7648086 | 0.84 | KDM4E (0.34) | — | |
| SCHEMBL7652393 | 0.83 | TAS2R14 (0.34) | GRIN1TAS2R14 | |
| SCHEMBL7198441 | 0.82 | AR (0.36) | GRIN1 | |
| SCHEMBL7648893 | 0.81 | TAS2R14 (0.31) | TAS2R14 | |
| SCHEMBL7068989 | 0.79 | AR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486143-B2 | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-11-26 | — | — | US | disclosed |
| US-20010031746-A1 | 6-amino- or 6-hydrazino-sulphonyl-3-quinolynyl-phosphonic acid compounds | LES LABORATOIRES SERVIER (FR) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031746-A1 | 6-amino- or 6-hydrazino-sulphonyl-3-quinolynyl-phosphonic acid compounds | CA6, P2RY6, FPR3 | GRIN1 801/4885TAS2R14 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.