Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DUT | P33316 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649393 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL75303 | 0.77 | LOXL2 (0.45) | KDM4EALDH1A1HPGD | |
| SCHEMBL1370758 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL18499080 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL30274765 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL11709052 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL7646960 | 0.73 | DAO (0.53) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL23610120 | 0.73 | DUT (0.44) | DUT | |
| SCHEMBL13349416 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL5946187 | 0.72 | SLC6A4 (0.52) | KDM4EALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |