Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 2/20 | 0.41 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652870 | 0.85 | KDM4E (0.44) | MAPTKDM4ELMNAHTTRAB9A | |
| SCHEMBL7652940 | 0.80 | KDM4E (0.51) | MAPTKDM4ELMNAHTTRAB9A | |
| SCHEMBL7652834 | 0.79 | ALKBH5 (0.48) | MAPTKDM4ELMNAHTTRAB9A | |
| SCHEMBL7652511 | 0.77 | KDM4E (0.51) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL7654106 | 0.75 | MGLL (0.44) | MAPTKDM4ELMNAHTTRAB9A | |
| SCHEMBL7650665 | 0.74 | KDM4E (0.64) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL7654354 | 0.74 | MEN1 (0.44) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL7652337 | 0.74 | KDM4E (0.44) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL7650494 | 0.74 | KDM4E (0.45) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL7657337 | 0.73 | MGLL (0.46) | MAPTKDM4ELMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |