Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652511 | 0.94 | KDM4E (0.51) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7650665 | 0.89 | KDM4E (0.64) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7654427 | 0.84 | KDM4E (0.60) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7653827 | 0.84 | KDM4E (0.48) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7652834 | 0.84 | ALKBH5 (0.48) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7649185 | 0.80 | MAPT (0.43) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7656234 | 0.79 | ALDH1A1 (0.53) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7660381 | 0.78 | KMT2A (0.54) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7652870 | 0.78 | KDM4E (0.44) | KDM4ECYP2C9HPGDALDH1A1MEN1 | |
| SCHEMBL7656771 | 0.78 | RAD51 (0.46) | KDM4ECYP2C9HPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |