SCHEMBL7649186

SCHEMBL7649186

Nc1ccc(Oc2ccc(Oc3ccc(N)c(Oc4cc(-c5ccc(N)c(O)c5)ccc4N)c3)cc2)cc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.55
CYP3A4 P08684 3/20 0.55
ALOX15 P16050 1/20 0.55
MMP2 P08253 1/20 0.42
MMP14 P50281 1/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NR4A1 P22736 1/20 0.41
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
POLB P06746 2/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 3/20 0.38
RAB9A P51151 1/20 0.38
TUBB4A P04350 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3321703 0.88 HSD17B10 (0.71) HSD17B10CYP3A4ALOX15ALDH1A1TSHR
SCHEMBL17267876 0.84 ALOX15 (0.71) HSD17B10CYP3A4ALOX15MMP2MMP14
SCHEMBL1348470 0.84 CYP3A4 (0.58) HSD17B10CYP3A4ALOX15MMP2MMP14
SCHEMBL716944 0.82 NR4A1 (0.58) HSD17B10CYP3A4ALOX15MMP2MMP14
SCHEMBL19809245 0.82 NR4A1 (0.58) HSD17B10CYP3A4ALOX15MMP2MMP14
SCHEMBL436522 0.80 NR4A1 (0.61) HSD17B10CYP3A4ALOX15MMP2MMP14
SCHEMBL30040301 0.80 NR4A1 (0.61) HSD17B10CYP3A4ALOX15MMP2MMP14
SCHEMBL9715074 0.79 MEN1 (0.56) CYP3A4ALDH1A1NR4A1MEN1KMT2A
SCHEMBL563890 0.79 MEN1 (0.61) HSD17B10CYP3A4ALOX15MMP2MMP14
Hydrochloric Acid SCHEMBL10770715 0.78 NR4A1 (0.58) HSD17B10CYP3A4ALOX15MMP2MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1262509-A1 IMIDE-BENZOXAZOLE POLYCONDENSATE AND PROCESS FOR PRODUCING THE SAME PI R & D Co., Ltd. (JP) 2002-12-04 EP claimed
EP-1262509-A1 IMIDE-BENZOXAZOLE POLYCONDENSATE AND PROCESS FOR PRODUCING THE SAME PI R & D Co., Ltd. (JP) 2002-12-04 EP disclosed