Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | PLG | P00747 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 6/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651047 | 0.90 | F10 (0.58) | F10MAPTKMT2AGAALMNA | |
| SCHEMBL1660858 | 0.88 | MAPT (0.61) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL1662623 | 0.86 | HDAC3 (0.60) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL5735860 | 0.86 | F10 (0.80) | F10KMT2AGAALMNAMEN1 | |
| SCHEMBL7074257 | 0.86 | F10 (0.53) | F10MAPTKMT2AGAALMNA | |
| SCHEMBL7649509 | 0.85 | GAA (0.61) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7649390 | 0.83 | KMT2A (0.56) | MAPTKMT2AGAALMNAMEN1 | |
| Acetic Acid SCHEMBL28744428 | 0.82 | F10 (0.74) | F10KMT2AGAALMNAMEN1 | |
| SCHEMBL10224655 | 0.82 | P2RY12 (0.59) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7074428 | 0.81 | PKM (0.62) | F10KMT2AGAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |