Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649409 | 0.90 | F10 (0.60) | F10MAPTLMNAGAAKMT2A | |
| SCHEMBL7649390 | 0.90 | KMT2A (0.56) | MAPTLMNAGAAKMT2AMEN1 | |
| SCHEMBL6737341 | 0.86 | F10 (0.77) | F10 | |
| SCHEMBL7072206 | 0.86 | F10 (0.52) | F10MAPTLMNAGAAKMT2A | |
| Hydrochloric Acid SCHEMBL5736315 | 0.86 | F10 (0.61) | F10MAPTLMNAGAA | |
| Hydrochloric Acid SCHEMBL5733561 | 0.85 | F10 (0.75) | F10 | |
| Acetic Acid SCHEMBL27550413 | 0.83 | F10 (0.71) | F10 | |
| SCHEMBL7074052 | 0.81 | F10 (0.56) | F10MAPTLMNAGAAKMT2A | |
| SCHEMBL7074610 | 0.80 | GAA (0.59) | F10MAPTLMNAGAAKMT2A | |
| SCHEMBL7074239 | 0.80 | F10 (0.63) | F10LMNACA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |