Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649962 | 1.00 | SNCA (0.60) | SNCAMAPTMAOBNFE2L2CYP19A1 | |
| SCHEMBL7655057 | 0.87 | SNCA (0.58) | SNCAMAPTMAOBCYP19A1HSP90AA1 | |
| SCHEMBL7655066 | 0.87 | SNCA (0.58) | SNCAMAPTMAOBCYP19A1HSP90AA1 | |
| SCHEMBL13890859 | 0.84 | SNCA (0.58) | SNCAMAPTMAOBNFE2L2CYP19A1 | |
| SCHEMBL9798094 | 0.84 | NFE2L2 (0.68) | SNCAMAPTMAOBNFE2L2CYP19A1 | |
| SCHEMBL13877019 | 0.84 | NFE2L2 (0.68) | SNCAMAPTMAOBNFE2L2CYP19A1 | |
| SCHEMBL10496489 | 0.84 | NFE2L2 (0.68) | SNCAMAPTMAOBNFE2L2CYP19A1 | |
| SCHEMBL7717261 | 0.82 | SNCA (0.53) | SNCAMAPTMAOBNFE2L2CYP19A1 | |
| SCHEMBL7717263 | 0.82 | SNCA (0.53) | SNCAMAPTMAOBNFE2L2CYP19A1 | |
| SCHEMBL7655913 | 0.82 | LMNA (0.55) | SNCAMAPTMAOBNFE2L2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |