Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982912 | 0.81 | HRH4 (0.41) | HRH4HRH3HTTCYP1A2CYP2D6 | |
| SCHEMBL921223 | 0.79 | HTR2A (0.42) | — | |
| SCHEMBL921312 | 0.74 | HTR1A (0.52) | HTT | |
| SCHEMBL727185 | 0.72 | CYP1A2 (0.62) | HRH4HRH3CYP1A2CYP2D6TBXAS1 | |
| SCHEMBL3959322 | 0.71 | CYP11B1 (0.45) | HRH4HRH3CYP1A2CYP2D6TBXAS1 | |
| Hydrochloric Acid SCHEMBL6177188 | 0.71 | HRH4 (0.49) | HRH4HRH3HTTCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11398017 | 0.71 | HTT (0.47) | HRH4HRH3HTTCYP1A2CYP2D6 | |
| SCHEMBL15888526 | 0.71 | CHRNA7 (0.47) | HRH4HRH3CYP1A2CYP2D6MMP2 | |
| SCHEMBL9923548 | 0.70 | HTT (0.68) | HRH4HRH3HTTCYP1A2CYP2D6 | |
| SCHEMBL6167380 | 0.70 | CYP11B1 (0.44) | HRH4HRH3CYP1A2CYP2D6TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492394-B1 | PROCOLLAGEN C-PROTEINASE INHIBITORS; TREATING FIBROTIC DISEASES | SYNTEX (U.S.A.) LLC | 2002-12-10 | — | — | US | disclosed |