SCHEMBL921312

SCHEMBL921312

Fc1[c]cccc1OCc1cccnc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.52
DRD2 P14416 2/20 0.52
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
IKBKB O14920 1/20 0.43
HTR6 P50406 1/20 0.43
GCK P35557 1/20 0.42
MAPK1 P28482 1/20 0.41
LMNA P02545 1/20 0.41
LRRK2 Q5S007 1/20 0.40
SLC6A4 P31645 1/20 0.40
PKM P14618 1/20 0.40
SGMS2 Q8NHU3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921724 0.83 SMN1; SMN2 (0.50) ALDH1A1MEN1HTTKMT2AIKBKB
SCHEMBL3211927 0.81 MAPT (0.50) HTR1ADRD2ALDH1A1MAPK1LMNA
SCHEMBL920470 0.78 ALDH1A1 (0.50) HTR1AALDH1A1POLBMEN1HTT
SCHEMBL921216 0.76 IDO1 (0.51) ALDH1A1MEN1KMT2AHTR6LMNA
SCHEMBL3315005 0.75 HTR1A (0.51) HTR1ADRD2ALDH1A1POLBIKBKB
SCHEMBL919103 0.75 DHFR (0.45) HTR1AALDH1A1POLBMEN1HTT
SCHEMBL919956 0.74 LMNA (0.47) ALDH1A1HTTMAPK1LMNA
SCHEMBL7285472 0.74 HTR1A (0.49) HTR1ADRD2ALDH1A1POLBMEN1
SCHEMBL921988 0.74 MAPT (0.46) HTR1APOLBMEN1HTTKMT2A
SCHEMBL7650149 0.74 HRH4 (0.41) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HTR1A 4648/4885DRD2 3451/4885ALDH1A1 2743/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 HTR1A 3327/4885DRD2 1003/4885ALDH1A1 4326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.