Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758569 | 0.84 | MAOB (0.41) | POLBSMN1; SMN2HSD17B10L3MBTL1TP53 | |
| SCHEMBL755566 | 0.84 | L3MBTL1 (0.38) | POLBSMN1; SMN2HSD17B10L3MBTL1TP53 | |
| SCHEMBL752322 | 0.83 | TP53 (0.47) | POLBSMN1; SMN2HSD17B10L3MBTL1TP53 | |
| SCHEMBL765461 | 0.78 | MAPT (0.51) | POLBHSD17B10KMT2ACYP2C19CYP1A2 | |
| SCHEMBL12206952 | 0.76 | RAB9A (0.38) | POLBSMN1; SMN2HSD17B10TP53KMT2A | |
| SCHEMBL16921547 | 0.75 | CA12 (0.38) | POLBSMN1; SMN2HSD17B10L3MBTL1TP53 | |
| SCHEMBL752081 | 0.75 | CA12 (0.38) | POLBSMN1; SMN2HSD17B10L3MBTL1TP53 | |
| SCHEMBL14562423 | 0.75 | RAB9A (0.45) | POLBL3MBTL1GAAKMT2ALMNA | |
| SCHEMBL4675011 | 0.74 | TP53 (0.35) | POLBSMN1; SMN2HSD17B10L3MBTL1TP53 | |
| SCHEMBL4675005 | 0.74 | TP53 (0.35) | POLBSMN1; SMN2HSD17B10L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |