SCHEMBL758569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752322	0.85	TP53 (0.47)	POLBKMT2AL3MBTL1TP53SMN1; SMN2
	SCHEMBL765016	0.84	POLB (0.43)	POLBKMT2ARAB9AL3MBTL1TP53
	SCHEMBL765461	0.81	MAPT (0.51)	POLBKMT2ANPSR1RAB9AHSD17B10
	SCHEMBL12206952	0.79	RAB9A (0.38)	POLBKMT2ANPSR1RAB9ATP53
	SCHEMBL755566	0.78	L3MBTL1 (0.38)	POLBKMT2ARAB9AL3MBTL1TP53
	SCHEMBL4675005	0.77	TP53 (0.35)	MAOBMAOAPOLBKMT2ARAB9A
	SCHEMBL4675011	0.77	TP53 (0.35)	MAOBMAOAPOLBKMT2ARAB9A
	SCHEMBL16921547	0.75	CA12 (0.38)	POLBKMT2ANPSR1RAB9AL3MBTL1
	SCHEMBL752081	0.75	CA12 (0.38)	POLBKMT2ANPSR1RAB9AL3MBTL1
	SCHEMBL765412	0.74	KMT2A (0.39)	MAOBMAOAPOLBKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.