Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | FPR1 | P21462 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6164678 | 0.82 | HDAC8 (0.74) | F10HDAC8ACEDPP8 | |
| SCHEMBL6168383 | 0.78 | MAPK1 (0.51) | KMT2AF10NPC1RAB9A | |
| SCHEMBL6168374 | 0.78 | MAPK1 (0.51) | KMT2AF10NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6169748 | 0.78 | KMT2A (0.49) | KMT2AF10HDAC8FPR1FPR2 | |
| SCHEMBL8410142 | 0.76 | TACR1 (0.52) | KMT2AF10 | |
| SCHEMBL18766825 | 0.76 | PSMB1 (0.54) | KMT2AF10NPC1RAB9AATM | |
| SCHEMBL5557838 | 0.75 | CTSS (0.61) | KMT2AACEFPR1FPR2DPP8 | |
| SCHEMBL7647840 | 0.75 | ADORA1 (0.47) | KMT2AF10HDAC8ACEHCRTR2 | |
| SCHEMBL18766822 | 0.74 | PSMB1 (0.80) | — | |
| SCHEMBL4372698 | 0.74 | CCKBR (0.45) | F10ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184370-A2 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2002-03-06 | — | — | EP | disclosed |
| US-6274584-B1 | PEPTIDE DERIVATIVES; BIOAVAILABILITY; ENZYME RESISTANCE; MILK AND WOOL PRODUCTION | NOVO NORDISK A/S (DK) | 2001-08-14 | — | — | US | disclosed |
| US-6127354-A | FOR TREATMENT OF GROWTH DISORDERS OR TO STIMULATE PRODUCTION OF WOOL OR MILK | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| US-5922770-A | NOVEL COMPOUNDS THAT STIMULATE THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY | NOVO NORDISK A/S (DK) | 1999-07-13 | — | — | US | disclosed |
| EP-0923539-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998003473-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-01-29 | — | — | WO | disclosed |