SCHEMBL7650247

SCHEMBL7650247

CCCC(C)(C)c1cc(OC)cc(-c2cc(OC)cc(C(C)(C)CCC)c2O)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CNR2 P34972 14/20 0.40
CNR1 P21554 12/20 0.40
TRPV1 Q8NER1 1/20 0.33
ABL1 P00519 1/20 0.33
ABCB1 P08183 1/20 0.33
BCR P11274 1/20 0.33
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
PTGS2 P35354 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7648531 0.86 CA1 (0.42) CA1CA2CNR2CNR1ABL1
SCHEMBL5080349 0.81 CA1 (0.60) CA1CA2CNR2CNR1ABL1
SCHEMBL29933298 0.77 CA2 (0.61) CA1CA2ABL1ABCB1BCR
SCHEMBL7645330 0.77 CA2 (0.61) CA1CA2ABL1ABCB1BCR
SCHEMBL17129735 0.76 ALDH1A1 (0.46) CA1CA2CNR2CNR1TRPV1
SCHEMBL8395315 0.75 CNR1 (0.38) CNR2CNR1
SCHEMBL19142342 0.74 CA1 (0.56) CA1CA2CNR2CNR1PTGS2
SCHEMBL7650252 0.73 CA1 (0.42) CA1CA2ABL1ABCB1BCR
SCHEMBL1835827 0.73 CNR2 (0.38) CA1CA2CNR2CNR1
SCHEMBL9652029 0.70 CA1 (0.53) CA1CA2CNR2CNR1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6486359-B1 Catalyst comprising a complex of a metal of subgroup viii based on a phosphinite ligand, and a method for hydroformylation BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed