Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | BCR | P11274 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645330 | 0.80 | CA2 (0.61) | CA1CA2ABL1ABCB1BCR | |
| SCHEMBL29933298 | 0.80 | CA2 (0.61) | CA1CA2ABL1ABCB1BCR | |
| SCHEMBL7648531 | 0.75 | CA1 (0.42) | CA1CA2ABL1ABCB1BCR | |
| SCHEMBL7650247 | 0.73 | CA1 (0.41) | CA1CA2ABL1ABCB1BCR | |
| SCHEMBL29602570 | 0.68 | CA2 (0.80) | CA1CA2PTGS2 | |
| SCHEMBL240515 | 0.68 | CA2 (0.80) | CA1CA2PTGS2 | |
| SCHEMBL7650206 | 0.67 | CA2 (0.42) | CA1CA2PTGS2 | |
| SCHEMBL7647539 | 0.67 | CA1 (0.59) | CA1CA2ABL1ABCB1BCR | |
| SCHEMBL11576252 | 0.67 | CYP2C9 (0.44) | CA1CA2PTGS2 | |
| SCHEMBL4575808 | 0.66 | CA1 (0.62) | CA1CA2ABL1ABCB1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486359-B1 | Catalyst comprising a complex of a metal of subgroup viii based on a phosphinite ligand, and a method for hydroformylation | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | disclosed |