Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653478 | 0.98 | HTR6 (0.36) | CELTDP1L3MBTL1HTR6PTGDR2 | |
| SCHEMBL11792179 | 0.77 | CYP1B1 (0.39) | CELTDP1L3MBTL1HTR6PTGDR2 | |
| SCHEMBL13004824 | 0.77 | ALDH1A1 (0.36) | CELTDP1L3MBTL1HTR6PTGDR2 | |
| SCHEMBL19284708 | 0.77 | HTR6 (0.56) | HTR6SLC6A4ADRB2HTR2C | |
| SCHEMBL11002147 | 0.77 | IDO1 (0.53) | TDP1PTGDR2 | |
| SCHEMBL7650801 | 0.77 | CYP1A2 (0.50) | CELTDP1L3MBTL1HTR6DRD2 | |
| SCHEMBL30735827 | 0.77 | HTR6 (0.56) | HTR6SLC6A4ADRB2HTR2C | |
| SCHEMBL7655573 | 0.77 | CXCR4 (0.41) | CELTDP1L3MBTL1HTR6PTGDR2 | |
| SCHEMBL574426 | 0.77 | TDP1 (0.36) | CELTDP1L3MBTL1HTR6PTGDR2 | |
| SCHEMBL168782 | 0.76 | SLC6A4 (0.54) | TDP1L3MBTL1DRD2SLC6A4CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |