Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | CEL | P19835 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | OGG1 | O15527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242148 | 0.81 | ALDH1A1 (0.38) | PDE5ADRD2SLC6A4CNR1CNR2 | |
| SCHEMBL164339 | 0.78 | PTGDR2 (0.39) | L3MBTL1CELPTGDR2SLC6A4PTGS2 | |
| SCHEMBL7650796 | 0.77 | CEL (0.36) | TDP1L3MBTL1PDE5AATMHTR6 | |
| SCHEMBL4075041 | 0.75 | CEL (0.35) | CEL | |
| SCHEMBL7653478 | 0.74 | HTR6 (0.36) | TDP1L3MBTL1PDE5AATMHTR6 | |
| SCHEMBL2100602 | 0.74 | ALDH1A1 (0.48) | TDP1 | |
| SCHEMBL29434197 | 0.74 | ALDH1A1 (0.48) | TDP1 | |
| SCHEMBL4070687 | 0.74 | ABCB1 (0.35) | CELPTGDR2PTGS2 | |
| SCHEMBL7176869 | 0.73 | CYP1B1 (0.40) | TDP1L3MBTL1PDE5AATMNPY5R | |
| SCHEMBL7176865 | 0.73 | ALDH1A1 (0.44) | TDP1L3MBTL1DRD2SLC6A4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969498-B2 | Compositions and method of inhibiting polymerization of vinyl-aryl monomers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-03-03 | — | — | US | disclosed |
| CN-103124745-B | Compositions and method of inhibiting polymerization of vinyl-aryl monomers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-10-29 | — | — | CN | disclosed |
| EP-2585490-B1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-07-02 | — | — | EP | disclosed |
| US-20130158203-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | CARNEGIE MELLON UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| CN-103124745-A | Compositions and method of inhibiting polymerization of vinyl-aryl monomers | DOW GLOBAL TECHNOLOGIES LLC | 2013-05-29 | — | — | CN | disclosed |
| EP-2585490-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | Dow Global Technologies LLC (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012018650-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158203-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | PCNA, MKI67, VCL | TDP1 2408/4885L3MBTL1 3607/4885PDE5A 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.