Pyridine

Pyridine

SCHEMBL7650859

[Cu].c1ccc(B(c2ccccc2)c2ccccc2)cc1.c1ccncc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NOTUM Q6P988 1/20 0.42
ORAI1 Q96D31 2/20 0.38
ORAI2 Q96SN7 2/20 0.38
ORAI3 Q9BRQ5 2/20 0.38
TRPV6 Q9H1D0 2/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
ENPP2 Q13822 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
PCSK9 Q8NBP7 1/20 0.38
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL394177 0.97 TSHR (0.50) TSHRNAPRTTDP1NOTUMORAI1
Pyridine SCHEMBL28276555 0.95 TSHR (0.47) TSHRNAPRTTDP1NOTUMORAI1
Pyridine SCHEMBL28135478 0.84 TSHR (0.38) TSHRNAPRTTDP1NOTUMORAI1
Pyrimidine SCHEMBL27574973 0.84 ATM (0.39) TSHRNAPRTTDP1NOTUMORAI1
Pyridine SCHEMBL1173296 0.83 NOTUM (0.54) TSHRNAPRTTDP1NOTUMMEN1
SCHEMBL125450 0.80 TRPV6 (0.53) TSHRTDP1ORAI1ORAI2ORAI3
SCHEMBL26077596 0.78 NOTUM (0.61) NOTUMSLC6A2SLC6A4SLC6A3NPC1
Pyridine SCHEMBL1173561 0.78 ORAI1 (0.45) TSHRNAPRTTDP1ORAI1ORAI2
Pyridine SCHEMBL1173460 0.78 TSHR (0.41) TSHRNAPRTTDP1ORAI1ORAI2
Pyridine SCHEMBL1173490 0.78 TDP1 (0.41) TSHRNAPRTTDP1ORAI1ORAI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775733-B1 ANTIFOULING PAINT COMPOSITION, COATING FILM MADE FROM THE COMPOSITION, ANTIFOULING METHOD USING THE COMPOSITION, AND HULLS OR SUBMARINE STRUCTURES COVERED WITH THE COATING FILM CHUGOKU MARINE PAINTS (JP) 2002-09-04 EP disclosed
US-6172132-B1 ANTIFOULING AGENT, FILM FORMING COPOLYMER OF AN (METH)ACRYLIC ACID ESTER AND A TRIALKYLSILYL (METH)ACRYLATE OF GIVEN FORMULA, AND CHLORINATED PARAFFIN OF 8-30 CARBON ATOMS AND GIVEN CHLORINE CONTENT; STORAGE STABILITY, CRACK RESISTANCE CHUGOKO MARINE PAINTS LTD (JP) 2001-01-09 US disclosed
US-6110990-A CRACKING RESISTANCE AND HAVING SELF-POLISHING PROPERTIES SUCH THAT ADHERENCE OF AQUATIC ORGANISM TO SHIP BOTTOMS, UNDERWATER STRUCTURES, FISHING NETS CAN EFFECTIVELY PREVENTED; STORAGE STABILITY CHUGOKU MARINE PAINTS LTD (JP) 2000-08-29 US disclosed
EP-0775733-A1 ANTIFOULING PAINT COMPOSITION, COATING FILM MADE FROM THE COMPOSITION, ANTIFOULING METHOD USING THE COMPOSITION, AND HULLS OR SUBMARINE STRUCTURES COVERED WITH THE COATING FILM CHUGOKU MARINE PAINTS, LTD. (JP) 1997-05-28 EP disclosed