Pyridine

Pyridine

SCHEMBL1173296

c1ccc(-c2ccc(B(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccccc4)cc3)cc2)cc1.c1ccncc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.54
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MGLL Q99685 1/20 0.48
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
NAPRT Q6XQN6 1/20 0.41
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
MAPT P10636 2/20 0.39
RAB9A P51151 2/20 0.39
HSD17B10 Q99714 2/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
CYP19A1 P11511 1/20 0.38
MEN1 O00255 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26077596 0.86 NOTUM (0.61) NOTUMCA1CA2MGLLSMN1; SMN2
Pyridine SCHEMBL394177 0.85 TSHR (0.50) NOTUMTSHRTDP1NAPRTNPC1
Pyridine SCHEMBL7650859 0.83 TSHR (0.47) NOTUMTSHRTDP1NAPRTNPC1
Pyridine SCHEMBL28276555 0.83 TSHR (0.47) NOTUMTSHRTDP1NAPRTNPC1
Biphenyl SCHEMBL28116352 0.83 NOTUM (0.77) NOTUMALDH1A1TSHRTDP1NAPRT
Biphenyl SCHEMBL27563723 0.83 NOTUM (0.77) NOTUMALDH1A1TSHRTDP1NAPRT
Biphenyl SCHEMBL126611 0.83 NOTUM (0.77) NOTUMALDH1A1TSHRTDP1NAPRT
Biphenyl SCHEMBL29136533 0.83 NOTUM (0.77) NOTUMALDH1A1TSHRTDP1NAPRT
SCHEMBL28186476 0.80 CYP2A6 (0.65) CA1CA2ALDH1A1SMN1; SMN2MAPT
Biphenyl SCHEMBL15052303 0.80 NOTUM (0.72) NOTUMALDH1A1TSHRTDP1NAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436173-B2 Boron compounds, their production processes, and functional electronic devices using same KYOTO UNIVERSITY (JP) 2013-05-07 US disclosed
US-20110046372-A1 NOVEL BORON COMPOUNDS, THEIR PRODUCTION PROCESSES, AND FUNCTIONAL ELECTRONIC DEVICES USING SAME Kyoto University and Nippon Shokubai Co., LTD. 2011-02-24 US disclosed
EP-2233490-A1 NOVEL BORON COMPOUND, METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRONIC DEVICE USING THE SAME Kyoto University (JP) 2010-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046372-A1 NOVEL BORON COMPOUNDS, THEIR PRODUCTION PROCESSES, AND FUNCTIONAL ELECTRONIC DEVICES USING SAME ETFB, SLC40A1, SLC19A1 NOTUM 1315/4885CA1 2908/4885CA2 2565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.