Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252566 | 0.90 | MAPT (0.39) | ALDH1A1HPGDCYP1A2MAPTMAPK1 | |
| SCHEMBL7650850 | 0.88 | MTNR1A (0.39) | GPR84ATMGAAALDH1A1KDM4E | |
| SCHEMBL11055022 | 0.86 | ATM (0.47) | GPR84ATMGAAALDH1A1KDM4E | |
| SCHEMBL7654463 | 0.85 | MTNR1A (0.37) | GPR84ATMGAAALDH1A1KDM4E | |
| SCHEMBL7649224 | 0.84 | MAPT (0.38) | GPR84ATMGAAALDH1A1KDM4E | |
| SCHEMBL7654083 | 0.83 | MAPT (0.40) | GPR84ATMGAAALDH1A1KDM4E | |
| SCHEMBL7653940 | 0.79 | ALDH1A1 (0.39) | GPR84ATMGAAALDH1A1KDM4E | |
| SCHEMBL27279895 | 0.77 | TLR8 (0.45) | ALDH1A1HPGDCYP1A2MAPTMAPK1 | |
| SCHEMBL7653944 | 0.77 | CYP1A2 (0.59) | GPR84ATMGAAALDH1A1KDM4E | |
| SCHEMBL20799527 | 0.75 | NQO2 (0.52) | GPR84GAAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |