Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370903 | 0.92 | KMT2A (0.46) | KMT2APTGS2PTGS1CES2CES1 | |
| SCHEMBL15201697 | 0.91 | KMT2A (0.53) | KMT2APTGS2PTGS1CES2CES1 | |
| SCHEMBL27881153 | 0.88 | PTGS1 (0.49) | KMT2APTGS2PTGS1CES2CES1 | |
| SCHEMBL5692490 | 0.86 | KMT2A (0.52) | KMT2APTGS2PTGS1CYP2D6SRC | |
| SCHEMBL18990763 | 0.85 | ALDH1A1 (0.53) | KMT2APTGS2PTGS1CES2CES1 | |
| SCHEMBL183940 | 0.84 | KMT2A (0.67) | KMT2APTGS2PTGS1LMNAL3MBTL1 | |
| SCHEMBL2430512 | 0.84 | KMT2A (0.50) | KMT2APTGS2PTGS1CYP2D6SRC | |
| SCHEMBL5537242 | 0.84 | KMT2A (0.67) | KMT2APTGS2PTGS1LMNAL3MBTL1 | |
| SCHEMBL5544986 | 0.84 | KMT2A (0.67) | KMT2APTGS2PTGS1LMNAL3MBTL1 | |
| SCHEMBL28225645 | 0.83 | ALDH1A1 (0.47) | KMT2APTGS2PTGS1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |