Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651108 | 0.92 | KMT2A (0.52) | KMT2APTGS1PTGS2CES2CES1 | |
| SCHEMBL15201697 | 0.84 | KMT2A (0.53) | KMT2APTGS1PTGS2CES2CES1 | |
| SCHEMBL10527197 | 0.82 | KMT2A (0.47) | KMT2APTGS1PTGS2ALDH1A1CYP3A4 | |
| SCHEMBL4202325 | 0.82 | KMT2A (0.47) | KMT2APTGS1PTGS2ALDH1A1CYP3A4 | |
| SCHEMBL1354811 | 0.81 | LMNA (0.52) | KMT2AALDH1A1CYP3A4CES2CES1 | |
| SCHEMBL27881153 | 0.81 | PTGS1 (0.49) | KMT2APTGS1PTGS2CES2CES1 | |
| SCHEMBL5692490 | 0.79 | KMT2A (0.52) | KMT2APTGS1PTGS2FAAHLMNA | |
| SCHEMBL30217969 | 0.79 | KMT2A (0.44) | KMT2AALDH1A1CYP3A4CES2CES1 | |
| Acetic Acid SCHEMBL17748817 | 0.78 | PTGS2 (0.63) | KMT2APTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL18990763 | 0.78 | ALDH1A1 (0.53) | KMT2APTGS1PTGS2ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87103559-A | Macrolide compounds, their production and use | — | 1988-01-27 | — | — | CN | claimed |
| EP-0419327-B1 | Amino acid derivatives, method for their preparation and their therapeutic application | BIOPROJET SOC CIV (FR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1991004246-A1 | METHOD FOR PREPARING AMINO ACID DERIVATIVES AND THERAPEUTICAL APPLICATIONS OF SAME | SOCIETE CIVILE BIOPROJET (FR) | 1991-04-04 | — | — | WO | disclosed |
| EP-0419327-A1 | Amino acid derivatives, method for their preparation and their therapeutic application | SOCIETE CIVILE BIOPROJET (FR) | 1991-03-27 | — | — | EP | disclosed |