SCHEMBL7651130

SCHEMBL7651130

C=CC=C(C=Cc1ccccc1)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HDAC3 O15379 2/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
PLIN1 O60240 2/20 0.50
LMNA P02545 2/20 0.50
RECQL P46063 2/20 0.50
PLIN5 Q00G26 2/20 0.50
ABHD5 Q8WTS1 2/20 0.50
F3 P13726 2/20 0.50
TNKS O95271 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
TNKS2 Q9H2K2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245521 0.92 ALDH1A1 (0.44) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL26079487 0.92 ALDH1A1 (0.44) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL19058802 0.92 MAPT (0.47) MAPTALDH1A1HDAC3HDAC4HDAC1
Butadiene SCHEMBL3762435 0.91 MAPT (0.50) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL5551883 0.89 HDAC3 (0.60) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL19872767 0.88 MAPT (0.44) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL19872825 0.88 GLA (0.42) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL7703255 0.86 MAOB (0.45) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL116598 0.86 LMNA (0.39) MAPTALDH1A1HDAC3HDAC4HDAC1
SCHEMBL6735916 0.86 MAPT (0.47) MAPTALDH1A1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1989009693-A1 ASPHALTIC FLASHING STICK GAF BUILDING MATERIALS CORPORATION (US) 1989-10-19 WO claimed
EP-3559135-B1 BINDER THAT IS SOLID AT ROOM TEMPERATURE TOTALENERGIES ONETECH (FR) 2023-11-15 EP disclosed
WO-2023076408-A1 MEDICAL TUBING AND FORMULATIONS THEREFOR CAREFUSION 303, INC. (US) 2023-05-04 WO disclosed
EP-3893952-A1 MULTILAYER SYNTHETIC RUBBER COMPOSITIONS Ineo-Tech SDN BHD (MY) 2021-10-20 EP disclosed
WO-2021076990-A1 MULTILAYER MEDICAL TUBING WITH ENHANCED ADHESION CAREFUSION 303, INC. (US) 2021-04-22 WO disclosed
WO-2020122704-A1 MULTILAYER SYNTHETIC RUBBER COMPOSITIONS INEO-TECH SDN BHD (MY) 2020-06-18 WO disclosed
EP-3559135-A1 BINDER THAT IS SOLID AT ROOM TEMPERATURE Total Marketing Services (FR) 2019-10-30 EP disclosed
WO-2018115729-A1 BINDER THAT IS SOLID AT ROOM TEMPERATURE TOTAL MARKETING SERVICES (FR) 2018-06-28 WO disclosed
EP-0952174-B1 Co-agglomeration of vinyl aromatic/diolefin copolymer with sulfur for polymer/asphalt admixtures BASF CORP (US) 2002-06-19 EP disclosed