Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001563 | 0.91 | — | — | |
| SCHEMBL20461 | 0.89 | — | — | |
| SCHEMBL5442827 | 0.89 | ALDH1A1 (0.43) | — | |
| SCHEMBL10348508 | 0.80 | — | — | |
| SCHEMBL8581776 | 0.80 | — | — | |
| SCHEMBL11353006 | 0.80 | — | — | |
| Magnesium SCHEMBL3899343 | 0.80 | — | — | |
| Charcoal, Activated SCHEMBL6544903 | 0.80 | — | — | |
| SCHEMBL1415964 | 0.80 | — | — | |
| SCHEMBL1663390 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489410-B1 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR POLYMERIZATION OF OLEFINS. IN ITS BROADEST FORM, THE METHOD OF PRODUCING THE SUPPORTED CATALYTIC COMPOSITION OF THE PRESENT INVENTION COMPRISES TREATING AN INORGANIC OR INORGANIC OXIDE | W. R. GRACE & CO.-CONN. | 2002-12-03 | — | — | US | claimed |
| EP-0830392-A1 | SUPPORTED CATALYST COMPOSITION FOR POLYMERIZATION OF OLEFINS | W.R. Grace & Co.-Conn. (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996040804-A1 | SUPPORTED CATALYST COMPOSITION FOR POLYMERIZATION OF OLEFINS | W.R. GRACE & CO.-CONN. (US) | 1996-12-19 | — | — | WO | claimed |