Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651450 | 1.00 | KMT2A (0.47) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6293485 | 0.88 | CYP3A4 (0.41) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6293484 | 0.88 | CYP3A4 (0.41) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL3160001 | 0.81 | KMT2A (0.58) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL3175249 | 0.80 | HPGD (0.57) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL3168918 | 0.78 | POLB (0.64) | KMT2AMEN1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL3159408 | 0.78 | FKBP1A (0.61) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10191949 | 0.76 | ALDH1A1 (0.58) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6297194 | 0.76 | MEN1 (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL14694131 | 0.74 | LMNA (0.40) | KMT2AMEN1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376527-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |