Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13950432 | 0.82 | MEN1 (0.37) | LMNACYP2A6CYP19A1MAPK1ALDH1A1 | |
| SCHEMBL7929166 | 0.78 | CA1 (0.32) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL16139495 | 0.76 | MEN1 (0.39) | LMNACYP2A6CYP19A1MAPK1ALDH1A1 | |
| SCHEMBL17288700 | 0.76 | — | — | |
| SCHEMBL7052956 | 0.76 | — | — | |
| SCHEMBL15391669 | 0.76 | MEN1 (0.38) | LMNAMAPK1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL789123 | 0.76 | CYP2A6 (0.38) | CYP2A6MAPK1ALDH1A1CA1CA2 | |
| SCHEMBL7940657 | 0.76 | ESR1 (0.39) | LMNAALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL6760551 | 0.76 | ACHE (0.38) | ALDH1A1CA1CA2TSHRTDP1 | |
| SCHEMBL18720495 | 0.76 | PTPN5 (0.36) | LMNAALDH1A1IDO1HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486351-B1 | Method for condensation of aromatic derivative(s) and a sulphinic derivative | RHODIA CHIMIE (FR) | 2002-11-26 | — | — | US | disclosed |